| Fairfield Inn by Marriott Orangeburg | 663 Citadel Road, Orangeburg, South Carolina |
| Hampton Inn Orangeburg, S.C. | I-26 Exit 145a, Orangeburg, South Carolina |
| Holiday Inn Express Hotel & Suites ORANGEBURG | 118 Sleep Inn Road, Orangeburg, South Carolina |
| Howard Johnson Express Inn - Orangeburg | 3608 Old St. Matthews Rd., Orangeburg, South Carolina |
| Orangeburg - Days Inn South | Route 2 Box 215, Orangeburg, South Carolina |
| Orangeburg-Days Inn North | 3691 St. Mathews Road, Orangeburg, South Carolina |
| Quality Inn & Suites | 1415 John C. Calhoun Dr., Orangeburg, South Carolina |
| Sleep Inn Orangeburg | 3689 St. Matthews Rd, Orangeburg, South Carolina |
